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Ribociclib succinate hydrate - CAS 1374639-79-8

Ribociclib succinate hydrate - CAS 1374639-79-8

MF-0033162-01

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Product Details

  • Bioactivity

    Ribociclib succinate hydrate is a highly specific CDK4/6 inhibitor (IC50s: 10 nM and 39 nM, respectively) . It also is over 1,000-fold less potent against the cyclin B/CDK1 complex.

  • Target

    CDK

  • Related Pathways

    Cell Cycle/Checkpoint

  • CAS Number

    1374552

  • Molecular Formula

    C27H38N8O6

  • Molecular Weight

    570.651

  • SMILES

    O.OC(=O)CCC(O)=O.CN(C)C(=O)c1cc2cnc(Nc3ccc(cn3)N3CCNCC3)nc2n1C1CCCC1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound