Ricinelaidic Acid - CAS 540-12-5

Ricinelaidic acid is a 12-hydroxy fatty acid and an antagonist of leukotriene B4 (LTB4) receptors (Ki = 2 μM in porcine neutrophil membranes) . It inhibits chemotaxis and calcium flux induced by LTB4 in isolated human neutrophils (IC50s = 10 and 7 μM, respectively) . Ricinelaidic acid (1 mg/kg, i.v.) inhibits bronchoconstriction induced by LTB4 in rats by 46%.

Others, Endogenous Metabolite, Calcium Channel, Leukotriene Receptor

Metabolism, GPCR/G Protein, Others, Membrane transporter/Ion channel

523

C18H34O3

298.46

[C@H](C/C=C/CCCCCCCC(O)=O)(CCCCCC)O

-20°C

Ice Packs

Small Compound