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RIP1 kinase inhibitor 7 - CAS 2428401-23-2
RIP1 kinase inhibitor 7 - CAS 2428401-23-2
SKU:MF-0147049-01
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$1,383.80 USD
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$1,383.80 USD
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Product Details
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Bioactivity
RIP1 Kinase Inhibitor 7 (Compound 41) serves as a potent inhibitory agent for receptor interacting protein 1 kinase (RIP1) with an IC50 of under 100 nM. Additionally, it demonstrates an EC50 ranging from 1 to 100 nM in cell necrosis assays [1].
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Target
RIP kinase
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Related Pathways
Apoptosis, NF-κB
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CAS Number
2428376
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Molecular Formula
C20H20FN3O
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Molecular Weight
337.39
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SMILES
C(=O)(N1C(CC=N1)C2=CC=CC=C2)N3CC(CC4=CC(F)=CC=C4)C3
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound