RIP3 activator 1 - CAS 1456899-52-7

RIP3 Activator 1 (compound C8) is an effective RIP3 activator that inhibits cell growth and induces necroptotic cell death (necroptosis) and autophagy through the RIP3/p62/Keap1 signaling pathway. Additionally, this compound enhances the expression of p-MLKL and promotes the accumulation of LC3-II and p62 proteins.

Autophagy, Necroptosis, RIP kinase

NF-κB, Autophagy, Apoptosis

1456840

C26H50N4O3

466.7

C(OC[C@@H]1OC[C@H](N)[C@H]1O)C2=CN(CCCCCCCCCCCCCCCCCC)N=N2

-20°C

Ice Packs

Small Compound