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RIPK1-IN-11 - CAS 2173557-02-1

RIPK1-IN-11 - CAS 2173557-02-1

SKU:MF-0139193-01

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  • Bioactivity

    RIPK1-IN-11 is an orally active RIPK1 inhibitor with a Kd value of 9.2 nM and an IC50 value of 67 nM. RIPK1-IN-11 inhibits necrosis in human and mouse cells and exhibits anti-inflammatory effects.

  • Target

    Others, RIP kinase

  • Related Pathways

    NF-κB, Apoptosis, Others

  • CAS Number

    2173557-02-1

  • Molecular Formula

    C23H24N4O4S

  • Molecular Weight

    452.53

  • SMILES

    N(C(=O)C1CC1)C=2SC=3C(N2)=CC=C(C3)C=4C=C(NC(OC5CCOCC5)=O)C(C)=NC4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound