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RIPK1-IN-11 - CAS 2173557-02-1
RIPK1-IN-11 - CAS 2173557-02-1
SKU:MF-0139193-01
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$1,383.80 USD
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$1,383.80 USD
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Product Details
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Bioactivity
RIPK1-IN-11 is an orally active RIPK1 inhibitor with a Kd value of 9.2 nM and an IC50 value of 67 nM. RIPK1-IN-11 inhibits necrosis in human and mouse cells and exhibits anti-inflammatory effects.
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Target
Others, RIP kinase
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Related Pathways
NF-κB, Apoptosis, Others
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CAS Number
2173557-02-1
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Molecular Formula
C23H24N4O4S
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Molecular Weight
452.53
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SMILES
N(C(=O)C1CC1)C=2SC=3C(N2)=CC=C(C3)C=4C=C(NC(OC5CCOCC5)=O)C(C)=NC4
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound