RIPK1-IN-19 - CAS 2763831-43-0

RIPK1-IN-19 is a selective and potent bimodal RIPK1 inhibitor with IC50=15 nM that protects against cell necrosis and works well in the tnf α-induced Systemic Inflammatory Response Syndrome (SIRS) model and imiquimod (IMQ) -induced psoriasis model.

RIP kinase

NF-κB, Apoptosis

2763831-43-0

0.9881

C28H25FN6O2

496.54

C(N[C@@H](C)C1=CC(F)=CC=C1)(=O)C=2C=3C(N(C)C2)=CC=C(C3)C4=CC=5N(C=C4)N=C(NC(=O)C6CC6)N5

-20°C

Ice Packs

Small Compound