RIPK1-IN-23 - CAS 3031534-16-1

RIPK1-IN-23 (compound 19) is an RIPK1 inhibitor with potent anti-necroptotic effects in HT-29 cells (EC50 = 1.7 nM) . Additionally, RIPK1-IN-23 exhibits anti-inflammatory properties.

Necroptosis, RIP kinase

Apoptosis, NF-κB

3031517

C27H22N6O3

478.5

CN1C=2C(=CC=C(C2)C3=CC=C(C#N)C=C3)OC[C@H](NC(=O)C=4NC(CC5=CC=CC=C5)=NN4)C1=O

-20°C

Ice Packs

Small Compound