RIPK1-IN-28 - CAS 2968509-28-4

RIPK1-IN-28 (compound 13) is an orally active inhibitor of RIPK1. It exhibits inhibitory effects on human I2.1 and Hepa1-6 cells, with IC50 values of 0.4 and 1.2 nM, respectively.

RIP kinase

NF-κB, Apoptosis

2968477

C27H24N4O4

468.504

CN1C=2C(OC[C@H](NC(=O)C3=NN(C(C)=CC3=O)C4=CC=CC=C4)C1=O)=CC=C(C#CC5CC5)C2

-20°C

Ice Packs

Small Compound