RIPK2-IN-1 - CAS 2245820-70-4

RIPK2-IN-1 (compound 18f) is a potent inhibitor of RIPK2 with an IC50 of 51 nM, and also inhibits ALK2 with an IC50 of 5 nM.

ALK, Others, RIP kinase

Angiogenesis, NF-κB, Others, Tyrosine Kinase/Adaptors, Apoptosis

2245746

C23H27N5O3S

453.56

NC1=C(C2=CC(NS(C)(=O)=O)=CC(OC)=C2)C=C(C=N1)C3=CC=C(C=C3)N4CCNCC4

-20°C

Ice Packs

Small Compound