RIPK2 IN 10W - CAS 2789711-40-4

The IC50 value of RIPK2 IN 10W for RIPK2 is 0.6 nM, which is more than 50000 times higher than RIPK1 (IC50>30 μ M) . RIPK2 IN 10W has high kinase selectivity, inhibits RIPK2, and prevents NOD induced cytokine production after stimulation with muramyl dipeptide (MDP) . RIPK2 as a therapeutic target has shown potential in treating inflammatory bowel disease.

NOD-like Receptor (NLR), RIP kinase, TNF

Apoptosis, Immunology/Inflammation, NF-κB

2789667

C19H22FN5

339.41

NC1=C2C(=CN(C2=NC=N1)[C@H]3CC[C@@H](N)CC3)C4=C(F)C=C(C)C=C4

-20°C

Ice Packs

Small Compound