RIPK2-IN-6 - CAS 2242432-02-4

RIPK2-IN-6 (Compound 15a) is an inhibitor of RIPK that specifically targets the phosphorylation of RIPK2, thereby suppressing the NF-κB and MAPK signaling pathways. It has demonstrated anti-inflammatory and anti-fibrotic activities in a mouse model of colitis induced by Dextran sodium sulfate.

NF-κB, p38 MAPK, RIP kinase

NF-κB, MAPK, Apoptosis

2242432-02-4

C26H21NO3

395.45

O=C1C2=C(OC=C2C)C3=CC=C4C=5C3=C1N(C5C(=O)CC4(C)C)CC=6C=CC=CC6

-20°C

Ice Packs

Small Compound