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RJG-2051 - CAS 2851993-77-4
RJG-2051 - CAS 2851993-77-4
SKU:MF-0114786-01
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Product Details
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Bioactivity
RJG-2051 is a selective covalent inhibitor of aldo-keto reductase family 1 member C3 (AKR1C3), with an IC50 value of 13 nM. It interferes with the metabolism of substrates such as androgens, estrogens, and prostaglandins through AKR1C3. RJG-2051 holds potential for cancer research.
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Target
Reductase
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Related Pathways
Metabolism, Endocrinology/Hormones
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CAS Number
2851912
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Molecular Formula
C26H31N5O4S
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Molecular Weight
509.62
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SMILES
O=C(C1=CC=C(C=C1)S(=O)(=O)N2N=C(N=C2)C3CCCCC3)N4CCN(C=5C=CC=CC5OC)CC4
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound