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Molfinity
RK-701 - CAS 2648855-18-7
RK-701 - CAS 2648855-18-7
SKU:MF-0146759-01
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$1,647.05 USD
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$1,647.05 USD
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Product Details
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Bioactivity
RK-701, a highly selective and non-genotoxic G9a inhibitor, exhibits an IC 50 value of 23-27 nM. It selectively up-regulates HbF, γ-Globin, and BGLT3 expression while down-regulating H3K9me2 expression. Additionally, RK-701 inhibits BCL11A and ZBTB7A.
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Target
Histone Methyltransferase, Others
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Related Pathways
Others, Chromatin/Epigenetic
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CAS Number
2648830
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Molecular Formula
C26H30N4O3
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Molecular Weight
446.54
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SMILES
CC=1C2=C(NC1C(N[C@H](C(NC3=CC=C(C#N)C=C3)=O)CCC4CC4)=O)CC(C)(C)CC2=O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound