RMC-7977 - CAS 2765082-12-8

RMC-7977 is a highly selective inhibitor of the active (GTP-bound) forms of KRAS, HRAS, and NRAS with anticancer activity for the study of solid tumors with KRAS G12C mutations.

ERK, Ras, AMPK, Raf, Apoptosis, PARP, Kras, S6 Kinase

DNA Damage/DNA Repair, MAPK, GPCR/G Protein, PI3K/Akt/mTOR signaling, Chromatin/Epigenetic, Apoptosis

2765082-12-8

0.9991

C47H60N8O6S

865.09

O=C1OCC(C)(C)CC=2C3=CC(=CC=C3N(C2C=4C=C(C=NC4C(OC)C)N5CCN(CC5)C6CC6)CC)C=7N=C(SC7)CC(NC(=O)C8C9COCC89)C(=O)N%10NC1CCC%10

-20°C

Ice Packs

Small Compound