RNA polymerase II-IN-1 - CAS 2891451-07-1

RNA polymerase II-IN-1 (compound 19iv), an amatoxin, selectively inhibits RNA polymerase II (Pol II) with an IC50 of 36.66 nM and exhibits heightened cytotoxicity towards cancer cells while reducing toxicity in normal cells compared to α-Amanitin [1].

DNA/RNA Synthesis

Cell Cycle/Checkpoint, DNA Damage/DNA Repair

2891451-07-1

C38H53N11O12S

887.96

-20°C

Ice Packs

Small Compound