RNAENFDRF - CAS 2429946-75-6

RNAENFDRF (βIIPKC624-632) conjugated to TAT47-57, a cell-permeable peptide, forms SAMβA, a rationally designed peptide that selectively antagonizes Mfn1-βIIPKC association. SAMβA acts as a selective inhibitor of mitofusin 1-βIIPKC association, demonstrating improved heart failure outcomes in rats [1].

PKC

Chromatin/Epigenetic, Cytoskeletal Signaling

2429865

C50H73N17O16

1168.22

[C@H](CC1=CC=CC=C1)(C(N[C@H](C(N[C@H](C(N[C@@H](CC2=CC=CC=C2)C(O)=O)=O)CCCNC(=N)N)=O)CC(O)=O)=O)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCCNC(=N)N)N)=O)CC(N)=O)=O)C)=O)CCC(O)=O)=O)CC(N)=O)=O

-20°C

Ice Packs

Peptide