RNF5 inhibitor inh-02 - CAS 324579-65-9

RNF5 inhibitor inh-02 is a selective inhibitor of the ubiquitin ligase RNF5/RMA1, which can significantly rescue F508del-CFTR (cystic fibrosis transmembrane conductance regulator with a deletion at position 508 of phenylalanine) and regulate ATG4B and paxillin, making it useful for studying cystic fibrosis (CF) .

ATG, E1/E2/E3 Enzyme

Ubiquitination, Autophagy

324505

0.9923

C23H20N4S

384.5

N=1SC(=NC(=NC=2C=CC=CC2)C=3C=CC=CC3)N(C1C)CC=4C=CC=CC4

-20°C

Ice Packs

Small Compound