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Molfinity

Ro 31-8220 Mesylate - CAS 138489-18-6

Ro 31-8220 Mesylate - CAS 138489-18-6

SKU:MF-0018265-01

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  • Bioactivity

    Ro 31-8220 Mesylate (Bisindolylmaleimide IX mesylate) is a pan-PKC inhibitor for PKC-α/βI/βII/γ/ε (IC50: 5/24/14/27/24 nM), and also shows potent inhibition against MSK1, MAPKAP-K1b, S6K1, and GSK3β.

  • Target

    PKC, JNK

  • Related Pathways

    Chromatin/Epigenetic, Cytoskeletal Signaling, MAPK

  • CAS Number

    138465

  • Purity

    0.9918

  • Molecular Formula

    C25H23N5O2S·CH4O3S

  • Molecular Weight

    553.65

  • SMILES

    CS(O)(=O)=O.Cn1cc(C2=C(C(=O)NC2=O)c2cn(CCCSC(N)=N)c3ccccc23)c2ccccc12

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound