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Molfinity

RO 46-8443 - CAS 175556-12-4

RO 46-8443 - CAS 175556-12-4

SKU:MF-0044792-01

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  • Bioactivity

    RO 46-8443 is the first non-peptide endothelin ETB receptor selective antagonist. RO 46-8443 displays up to 2000-fold selectivity for ETB receptors both in terms of binding inhibitory potency and functional inhibition.

  • Target

    Endothelin Receptor

  • Related Pathways

    GPCR/G Protein

  • CAS Number

    175540

  • Purity

    0.9977

  • Molecular Formula

    C31H35N3O8S

  • Molecular Weight

    609.69

  • SMILES

    COc1ccc(cc1)-c1nc(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)c(Oc2ccccc2OC)c(OC[C@H](O)CO)n1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound