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RO 46-8443 - CAS 175556-12-4
RO 46-8443 - CAS 175556-12-4
SKU:MF-0044792-01
Regular price
$35.41 USD
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$35.41 USD
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Product Details
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Bioactivity
RO 46-8443 is the first non-peptide endothelin ETB receptor selective antagonist. RO 46-8443 displays up to 2000-fold selectivity for ETB receptors both in terms of binding inhibitory potency and functional inhibition.
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Target
Endothelin Receptor
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Related Pathways
GPCR/G Protein
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CAS Number
175540
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Purity
0.9977
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Molecular Formula
C31H35N3O8S
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Molecular Weight
609.69
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SMILES
COc1ccc(cc1)-c1nc(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)c(Oc2ccccc2OC)c(OC[C@H](O)CO)n1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound