Molfinity

Ro 5126766 - CAS 946128-88-7

SKU:MF-0012931-01

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Size 1 mg 2 mg 5 mg 1 mL - 10 mM (in DMSO) 10 mg 25 mg 50 mg 100 mg

Product Details

Bioactivity
RO5126766 (CH5126766) is a dual RAF/MEK inhibitor with IC50 of 8.2 nM, 19 nM, 56 nM, and 160 nM for BRAF V600E, BRAF, CRAF, and MEK1, respectively. Phase 1.
Target
Raf, MEK
Related Pathways
MAPK
CAS Number
946033
Purity
0.9881
Molecular Formula
C21H18FN5O5S
Molecular Weight
471.46
SMILES
CNS(=O)(=O)Nc1nccc(Cc2c(C)c3ccc(Oc4ncccn4)cc3oc2=O)c1F
Storage Temperature
-20°C
Shipping Conditions
Ice Packs
Category
Small Compound