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Ro 67-7476 - CAS 298690-60-5
Ro 67-7476 - CAS 298690-60-5
SKU:MF-0012425-01
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$32.42 USD
Regular price
$19.50 USD
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$32.42 USD
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Product Details
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Bioactivity
Ro 67-7476 is a positive allosteric modulator of mGluR1, which can enhance the calcium release induced by glutamate in HEK293 cells expressing rat mGluR1a. The EC50 is 60.1 nM. It is a P-ERK1/2 agonist, and can activate ERK1/2 phosphorylation without the addition of exogenous glutamate (EC50 = 163.3 nM) .
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Target
GluR
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Related Pathways
Neuroscience
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CAS Number
298690-60-5
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Purity
0.9969
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Molecular Formula
C17H18FNO2S
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Molecular Weight
319.39
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SMILES
Cc1ccc(cc1)S(=O)(=O)N1CCC[C@H]1c1ccc(F)cc1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound