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Molfinity

Ro 67-7476 - CAS 298690-60-5

Ro 67-7476 - CAS 298690-60-5

SKU:MF-0012425-01

Regular price $32.42 USD
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  • Bioactivity

    Ro 67-7476 is a positive allosteric modulator of mGluR1, which can enhance the calcium release induced by glutamate in HEK293 cells expressing rat mGluR1a. The EC50 is 60.1 nM. It is a P-ERK1/2 agonist, and can activate ERK1/2 phosphorylation without the addition of exogenous glutamate (EC50 = 163.3 nM) .

  • Target

    GluR

  • Related Pathways

    Neuroscience

  • CAS Number

    298690-60-5

  • Purity

    0.9969

  • Molecular Formula

    C17H18FNO2S

  • Molecular Weight

    319.39

  • SMILES

    Cc1ccc(cc1)S(=O)(=O)N1CCC[C@H]1c1ccc(F)cc1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound