Ro 90-7501 - CAS 293762-45-5

Ro 90-7501 is an amyloid β42 (Aβ42) protofibrillar and TPR-dependent PP5 inhibitor, a novel radiosensitizer for cervical cancer cells, which inhibits ATM phosphorylation, promotes apoptosis, and induces cell-cycle arrest. Ro 90-7501 also exhibits antiviral activity and potential anticancer activity by inhibiting ATM phosphorylation and DNA repair, and by inhibiting HCMV.

ATM/ATR, Gamma-secretase, Beta Amyloid, Phosphatase, Apoptosis

Apoptosis, Metabolism, Stem Cells, DNA Damage/DNA Repair, Proteases/Proteasome, Neuroscience, PI3K/Akt/mTOR signaling

293712

0.998

C20H16N6

340.38

NC1=CC=C(C=C1)C1=NC2=C(N1)C=C(C=C2)C1=NC2=C(N1)C=C(N)C=C2

-20°C

Ice Packs

Small Compound