RO27-3225 TFA - CAS 1373926-49-8

RO27-3225, also known as RO273225 is a melanocortin type 4 receptor agonist with EC50 = 1 nM. It may alleviate intestinal dysfuntion and brain damage. It has been investigated for an anti-obesity medication. Ro 27-3225 shows some activity at the MC1 receptor. Ro 27-3225 reverses hemorrhagic shock, reduces multiple organ damage, and improves survival.

TNF, Melanocortin Receptor, Interleukin, Others

Apoptosis, Others, GPCR/G Protein, Immunology/Inflammation, Neuroscience

1373869

C41H53F3N12O8

898.9462

OC(=O)C(F)(F)F.CCCC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N(C)CC(N)=O

-20°C

Ice Packs

Small Compound