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Molfinity

RO8994 - CAS 1309684-94-3

RO8994 - CAS 1309684-94-3

MF-0093154-01

$35.41 USD
$35.41 USD
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Product Details

  • Bioactivity

    RO8994 is a highly effective and specific inhibitor of spiroindolinone small-molecule MDM2, with IC50 of 20 nM (MTT proliferation assays) and 5 nM (HTRF binding assays) .

  • Target

    Apoptosis, E1/E2/E3 Enzyme, Mdm2, MDM-2/p53, p53

  • Related Pathways

    Apoptosis, Ubiquitination

  • CAS Number

    1309587

  • Purity

    0.9944

  • Molecular Formula

    C31H31Cl2FN4O4

  • Molecular Weight

    613.51

  • SMILES

    COc1cc(ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@]2([C@H]1c1cccc(Cl)c1F)C(=O)Nc1cc(Cl)ccc21)C(N)=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound