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Molfinity
ROCK-IN-10 - CAS 1038549-25-5
ROCK-IN-10 - CAS 1038549-25-5
SKU:MF-0119895-01
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Product Details
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Bioactivity
ROCK-IN-10 (compound 50) serves as a powerful inhibitor of ROCK, exhibiting IC50 values of 6 nM for ROCK1 and 4 nM for ROCK2, respectively. It demonstrates over 100-fold selectivity towards ROCK1 and ROCK2 when compared to other kinases [1].
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Target
Others, ROCK
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Related Pathways
Stem Cells, Cytoskeletal Signaling, Cell Cycle/Checkpoint, Others
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CAS Number
1038549-25-5
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Molecular Formula
C25H25N5O3
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Molecular Weight
443.507
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SMILES
NC(=O)c1ccc(NC(=O)NCc2cccc(c2)C(=O)Nc2ccc3CCNCc3c2)cc1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound