Rodatristat ethyl - CAS 1673571-51-1

Rodatristat ethyl (KAR5585) is a groundbreaking, orally active, and potent inhibitor of tryptophan hydroxylase 1 (TPH1) that significantly reduces 5-hydroxytryptamine (5-HT) levels and decreases pulmonary arterial hypertension (PAH) at low concentrations.

Hydroxylase, 5-HT Receptor

Neuroscience, GPCR/G Protein, Metabolism

1673519

C29H31ClF3N5O3

590.04

C(OCC)(=O)[C@@H]1CC2(CCN(CC2)C=3C=C(O[C@@H](C(F)(F)F)C4=C(C=C(Cl)C=C4)C5=CC=CC=C5)N=C(N)N3)CN1

-20°C

Ice Packs

Small Compound