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Molfinity

Roflumilast - CAS 162401-32-3

Roflumilast - CAS 162401-32-3

MF-0004311-01

$47.38 USD
$47.38 USD
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Product Details

  • Bioactivity

    Roflumilast (APTA 2217) is an orally available, long-acting inhibitor of phosphodiesterase (PDE) type 4 (PDE4), with anti-inflammatory and potential antineoplastic activities. Upon administration, roflumilast and its active metabolite roflumilast N-oxide selectively and competitively bind to and inhibit PDE4, which leads to an increase of both intracellular levels of cyclic-3', 5'-adenosine monophosphate (cAMP) and cAMP-mediated signaling.

  • Target

    PDE, RSV

  • Related Pathways

    Metabolism, Microbiology/Virology

  • CAS Number

    162366

  • Purity

    >99.99%

  • Molecular Formula

    C17H14Cl2F2N2O3

  • Molecular Weight

    403.21

  • SMILES

    O(CC1CC1)C2=C(OC(F)F)C=CC(C(NC=3C(Cl)=CN=CC3Cl)=O)=C2

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound