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Roniciclib - CAS 1223498-69-8

Roniciclib - CAS 1223498-69-8

SKU:MF-0033979-01

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  • Bioactivity

    Roniciclib (BAY 1000394) is a potent pan-CDK inhibitor and a novel oral cytotoxic agent. Roniciclib inhibits the activity of cell-cycle CDKs CDK1, CDK2, CDK3, CDK4, and of transcriptional CDKs CDK7 and CDK9 with IC (50) values in the range between 5 and 25 nmol/L.

  • Target

    CDK

  • Related Pathways

    Cell Cycle/Checkpoint

  • CAS Number

    1223421

  • Purity

    0.9884

  • Molecular Formula

    C18H21F3N4O3S

  • Molecular Weight

    430.44

  • SMILES

    C[C@@H](O)[C@@H](C)Oc1nc(Nc2ccc(cc2)[S@](=N)(=O)C2CC2)ncc1C(F)(F)F

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound