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ROR agonist-1 - CAS 2361528-74-5
ROR agonist-1 - CAS 2361528-74-5
SKU:MF-0026915-01
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$1,383.80 USD
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$1,383.80 USD
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Product Details
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Bioactivity
ROR agonist-1 is a potent and orally bioavailable inverse agonist of the retinoic acid receptor-related orphan receptor C2 (RORC2), demonstrating inhibition of IL-17A production from human primary TH17 cells with a pIC50 of 7.5.
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Target
Others, ROR
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Related Pathways
Metabolism, Others
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CAS Number
2361449
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Molecular Formula
C21H20F6N2O5S
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Molecular Weight
526.45
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SMILES
C(C(F)(F)F)(C(F)(F)F)(O)C1=CC=C(NC([C@H](NC(C)=O)C2=CC=C(S(CC)(=O)=O)C=C2)=O)C=C1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound