Molfinity

RORγt/DHODH-IN-1 - CAS 2764662-15-7

SKU:MF-0140690-01

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Product Details

Bioactivity
RORγt/DHODH-IN-1 (compound (R) -14d) is a potent, orally active dual inhibitor of RORγt (IC50: 0.083 μM) and DHODH (IC50: 0.172 μM), exhibiting significant in vivo anti-inflammatory effects.
Target
Others, Dehydrogenase, ROR
Related Pathways
Others, Metabolism
CAS Number
2764640
Molecular Formula
C24H26ClF6N3O3S
Molecular Weight
585.99
SMILES
N(C1=NC2=C(S1)CCC[C@H]2O)C3=C(C)C(OC4CCN(C(CC(C(F)(F)F)C(F)(F)F)=O)CC4)=CC(Cl)=C3
Storage Temperature
-20°C
Shipping Conditions
Ice Packs
Category
Small Compound