ROS 234 - CAS 184576-87-2

ROS 234 is a highly effective H3 antagonist, demonstrating a strong binding affinity (pK B) of 9.46 for the Guinea-pig ileum H3 receptor and a pKi of 8.90 for the Rat cerebral cortex H3 receptor. Additionally, it exhibits an ex vivo ED50 of 19.12 mg/kg (ip) in the Rat cerebral cortex. It should be noted that ROS 234 demonstrates limited central access, as reported in [1] and [2].

Others, Histamine Receptor

Others, Immunology/Inflammation, Neuroscience, GPCR/G Protein

184487

C13H15N5

241.29

N(CCCC1=CN=CN1)C=2NC=3C(N2)=CC=CC3

-20°C

Ice Packs

Small Compound