Rosiglitazone potassium - CAS 316371-84-3

Rosiglitazone (BRL 49653) potassium, a potent and selective PPARγ agonist (EC 50: 60 nM, Kd: 40 nM) administered orally, also acts as an activator of TRPC5 (EC 50: 30 μM) and an inhibitor of TRPM3. Widely used in research, it has shown promise in investigating obesity, diabetes, senescence, and ovarian cancer [1] [2] [4] [7].

Ferroptosis, Apoptosis, Autophagy, Others, PPAR, TRP/TRPV Channel

Metabolism, Autophagy, Membrane transporter/Ion channel, Apoptosis, DNA Damage/DNA Repair, Others

316371-84-3

C18H18KN3O3S

395.52

[K+].CN(CCOc1ccc(CC2SC(=O)[N-]C2=O)cc1)c1ccccn1

-20°C

Ice Packs

Small Compound