Rosiglitazone sodium - CAS 316371-83-2

Rosiglitazone sodium is an effective and selective PPARγ activator, with EC50 values of 30 nM for PPARγ1, 100 nM for PPARγ2, and 60 nM for PPARγ. It also has an approximate Kd of 40 nM for PPARγ. Additionally, Rosiglitazone sodium acts as a regulator of TRP channels, inhibiting the activities of TRPM2 and TRPM3, while activating TRPC5.

Autophagy, PPAR, TRP/TRPV Channel

Membrane transporter/Ion channel, Autophagy, Metabolism, DNA Damage/DNA Repair

316286

C18H18N3NaO3S

379.41

O=C1SC(CC2=CC=C(C=C2)OCCN(C)C3=NC=CC=C3)C([N-]1)=O.[Na+]

-20°C

Ice Packs

Small Compound