Rosolutamide - CAS 1039760-91-2

Rosolutamide (ALZ-003) is a curcumin analog, an orally active Nrf1 and Nrf2 activator.Rosolutamide modulates oxidative homeostasis, improves mitochondrial function and promotes autophagy, reduces mutant protein aggregation, and decreases intracellular/mitochondrial reactive oxygen species (ROS) levels.Rosolutamide has been used in the study of neurodegeneration such as spinal cerebellar ataxia and Huntington disease. neurodegenerative diseases such as Huntington's disease. Regulates oxidative homeostasis.

HSP, Androgen Receptor, Mitophagy, Nrf2

Cytoskeletal Signaling, Endocrinology/Hormones, Metabolism, Autophagy, Immunology/Inflammation

1039667

0.9936

C28H32O6

464.55

C(CC1CCC1)(C(/C=C/C2=CC(OC)=C(OC)C=C2)=O)C(/C=C/C3=CC(OC)=C(OC)C=C3)=O

-20°C

Ice Packs

Small Compound