Rottlerin - CAS 82-08-6

Rottlerin (NSC-56346) is a natural product purified from Mallotus Philippinensis and is a specific PKC inhibitor (IC50: PKCδ of 3-6 μM, PKCα, β, γ of 30-42 μM, PKCε, η, ζ of 80-100 μM) . Rottlerin causes apoptosis via caspase 3 activation.

HIV Protease, Apoptosis, CaMK, Autophagy, PKC, PKA

Neuroscience, Apoptosis, Autophagy, Microbiology/Virology, Cytoskeletal Signaling, Chromatin/Epigenetic, Proteases/Proteasome, Tyrosine Kinase/Adaptors

82-08-6

0.9944

C30H28O8

516.54

CC(=O)c1c(O)c(C)c(O)c(Cc2c(O)c3C=CC(C)(C)Oc3c(C(=O)\C=C\c3ccccc3)c2O)c1O

-20°C

Ice Packs

Natural Product