Roxatidine - CAS 78273-80-0

Roxatidine, the active metabolite of Roxatidine acetate hydrochloride, serves as a histamine H2-receptor antagonist and exhibits anti-ulcer properties. It functions by suppressing the release of histamine, thereby inhibiting proton secretion, and also reduces the production of VEGF-1, a key indicator of inflammation and angiogenesis. This compound demonstrates an anti-allergic inflammatory effect [1].

Others, p38 MAPK, Histamine Receptor, NF-κB, Caspase

NF-κB, Others, Immunology/Inflammation, Proteases/Proteasome, Apoptosis, MAPK, GPCR/G Protein, Neuroscience

78193

C17H26N2O3

306.4

C(C1=CC(OCCCNC(CO)=O)=CC=C1)N2CCCCC2

-20°C

Ice Packs

Small Compound