RP-220 - CAS 1541177-35-8

RP-220 is a peptide that targets the NLRP3 enzyme and exhibits anti-inflammatory and anti-apoptotic properties. It inhibits apoptosis of renal tubular epithelial cells caused by alkaline damage by activating the MAPK signaling pathway. In mouse models of acute kidney injury (AKI), RP-220 significantly reduces NLRP3 expression, macrophage infiltration, and renal tissue damage. Additionally, RP-220 is applicable in research on systemic lupus erythematosus (SLE) and its complication lupus nephritis (LN) .

P38 MAPK, Apoptosis, NOD-like Receptor (NLR)

MAPK, Apoptosis, Immunology/Inflammation

1541177-35-8

C98H166N30O32S

2308.61

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-20°C

Ice Packs

Peptide