Rp-Adenosine-5'-O- (1-thiodiphosphate) sodium - CAS 2005478-89-5

Rp-Adenosine-5'-O- (1-thiodiphosphate) (Rp-ADP-α-S), a sulfur-containing isomer of the nucleotide derivative ADP-α-S, acts as an inhibitor of phosphorylase kinase with an inhibition constant (Ki) of 0.53 μM. This compound also induces aggregation in isolated human platelets with an effective concentration (EC50) of 20 μM and promotes relaxation in guinea pig taenia coli that has been precontracted with carbamoylcholine, with an EC50 of 58.9 μM.

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2005478-89-5

C10H12N5O9P2S.3Na

509.21

O[C@@H]1[C@@H](CO[P@](OP([O-])([O-])=O)([S-])=O)O[C@@H](N2C3=NC=NC(N)=C3N=C2)[C@@H]1O.[Na+].[Na+].[Na+]

-20°C

Ice Packs

Small Compound