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RSK-IN-2 - CAS 3011713-80-4
RSK-IN-2 - CAS 3011713-80-4
SKU:MF-0114768-01
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Product Details
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Bioactivity
RSK-IN-2 (Compound 3e) is an inhibitor of RSK, showing IC50 values of 37.89 nM for RSK2, 30.78 nM for RSK1, 20.51 nM for RSK3, and 91.28 nM for RSK4. It suppresses tumor cell proliferation, induces apoptosis, and causes cell cycle arrest at the G2/M phase.
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Target
Apoptosis, S6 Kinase
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Related Pathways
PI3K/Akt/mTOR signaling, Apoptosis, MAPK
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CAS Number
3011629
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Molecular Formula
C25H30ClN7O3
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Molecular Weight
512.004
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SMILES
O=C(NCCO)C=1C=CC=CC1NC2=NC(=NC=C2Cl)NC3=CC=C(C=C3OC)N4CCN(C)CC4
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound