RSK2-IN-4 - CAS 62001-32-5

RSK2-IN-4 (Compound 10) is an inhibitor of RSK2, showing an inhibition rate of 13.73% on RSK2 activity at a concentration of 10 μM. It binds to the ATP binding site of RSK2 within the NTKD (N-terminal kinase domain), with the electron-donating group at the para position of the phenyl ring being crucial for its inhibitory activity.

S6 Kinase

MAPK, PI3K/Akt/mTOR signaling

61964

C13H11ClN4

258.706

ClC1=CC=C(C=C1)NCN2N=NC=3C=CC=CC32

-20°C

Ice Packs

Small Compound