RSV L-protein-IN-5 - CAS 851658-28-1

RSV L-protein-IN-5 (Compound E) serves as a potent inhibitor of the Respiratory Syncytial Virus (RSV), with an EC50 value of 0.1 μM. It targets RSV polymerase with an IC50 of 0.66 μM and impedes RSV mRNA synthesis through the inhibition of transcript guanylation. The compound demonstrates moderate cytotoxicity, with a CC50 of 10.7 μM in HEp-2 cells, and effectively reduces viral titers in mouse models of RSV infection [1].

RSV

Microbiology/Virology

851629

C31H36N6O4

556.66

O=C1C=2C3=C(N=C(N3)C=4N=C(C)C=CC4)C(N)=CC2C(C)(C)C(=O)N1CCCNCCC5=CC(OC)=C(OC)C=C5

-20°C

Ice Packs

Small Compound