Molfinity
RT2 - CAS 1539295-33-4
RT2 - CAS 1539295-33-4
SKU:MF-0127257-01
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Product Details
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Bioactivity
RT2 is a cationic amphiphilic antimicrobial peptide rich in tryptophan that primarily targets lipopolysaccharides (LPS) on bacterial surfaces and intracellular DNA. By binding to surface LPS, RT2 interacts with cytoplasmic membrane phospholipids, enabling rapid penetration of the bacterial cell membrane and subsequent binding to cytoplasmic components such as DNA, exerting its antibacterial effects. RT2 holds potential for research into acute and chronic infections caused by planktonic bacteria.
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Target
Antibacterial
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Related Pathways
Microbiology/Virology
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CAS Number
1539295-33-4
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Molecular Formula
C126H165N39O20
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Molecular Weight
2545.91
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SMILES
C([C@@H](C(N[C@@H](CC=1C=2C(NC1)=CC=CC2)C(N[C@H](C(N[C@H](C(N[C@@H](CC=3C=4C(NC3)=CC=CC4)C(N[C@@H](CC=5C=6C(NC5)=CC=CC6)C(N)=O)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)=O)NC([C@@H](NC([C@H](CC=7C=8C(NC7)=CC=CC8)NC([C@H](CC=9C=%10C(NC9)=CC=CC%10)NC([C@@H](NC([C@H](CC%11=CC=C(O)C=C%11)NC([C@@H](NC(=O)[C@H]%12N(C([C@@H](NC([C@@H](NC(CNC([C@H](CC(N)=O)N)=O)=O)C(C)C)=O)CCC(N)=O)=O)CCC%12)CCCCN)=O)=O)CCCNC(=N)N)=O)=O)=O)CCCNC(=N)N)=O)C=%13C=%14C(NC%13)=CC=CC%14
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Peptide