Molfinity
RTDLDSLRTYTL - CAS 222557-93-9
RTDLDSLRTYTL - CAS 222557-93-9
SKU:MF-0126436-01
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Product Details
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Bioactivity
RTDLDSLRTYTL is a high-affinity and specific inhibitor of Alpha (v) beta (6) integrin (avb6) . By binding to the avb6 integrin, this peptide sequence activates T cell cytotoxicity and cytokine production, such as interferon-γ. Through the design of chimeric T cell antigen receptors (CAR), RTDLDSLRTYTL enables T cells to be redirected, allowing them to specifically recognize and attack tumor cells. It is used in research for cancer immunotherapy and the development of targeted drugs.
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Target
Integrin
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Related Pathways
Cytoskeletal Signaling
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CAS Number
222557-93-9
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Molecular Formula
C62H104N18O22
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Molecular Weight
1453.6
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SMILES
[C@@H](CC1=CC=C(O)C=C1)(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCCNC(=N)N)N)=O)[C@@H](C)O)=O)CC(O)=O)=O)CC(C)C)=O)CC(O)=O)=O)CO)=O)CC(C)C)=O)CCCNC(=N)N)=O)[C@@H](C)O)=O)C(N[C@H](C(N[C@@H](CC(C)C)C(O)=O)=O)[C@@H](C)O)=O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Peptide