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Molfinity

RTI-7470-44 - CAS 825658-63-7

RTI-7470-44 - CAS 825658-63-7

MF-0138094-01

$853.79 USD
$853.79 USD
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Product Details

  • Bioactivity

    RTI-7470-44 is a potent and selective human trace amine-associated receptor 1 (hTAAR1) antagonist (IC50: 8.4 nM) that crosses the blood-brain barrier. RTI-7470-44 increases the spontaneous firing rate of dopaminergic neurons in the ventral tegmental area (VTA) of the midbrain in mice. RTI-7470-44 can be used to study schizophrenia, drug addiction and Parkinson's disease (PD) .

  • Target

    Others

  • Related Pathways

    Others

  • CAS Number

    825588

  • Molecular Formula

    C19H11ClF3N5OS

  • Molecular Weight

    449.84

  • SMILES

    FC(F)(F)c1cc(nc(SCC(=O)Nc2ncccn2)c1C#N)-c1ccc(Cl)cc1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound