RTIL 13 - CAS 1009376-10-6

RTIL 13 is a highly effective inhibitor of dynamin GTPase, exhibiting an IC50 value of 2.3 μM for dynamin I GTPase. Furthermore, it selectively interacts with the pleckstrin homology lipid binding domain. This compound effectively suppresses both receptor-mediated and synaptic vesicle endocytosis, demonstrating IC50 values of 9.3 μM and 7.1 μM, respectively.

Others, Ras

MAPK, GPCR/G Protein, Others

1009360

C30H55BrN2O3

571.685

[Br-].[H][C@]12CC[C@]([H])(O1)[C@]1([H])C(=O)N(CC[N+](C)(C)CCCCCCCCCCCCCCCCCC)C(=O)[C@]21[H] |THB:36:38:7:3.4,10:8:7:3.4|

-20°C

Ice Packs

Small Compound