RU-0415529 - CAS 1358734-35-6

RU-0415529 is an orally active inhibitor of SARS-CoV-2 non-structural protein 14 (NSP14), with an IC50 of 356 nM. It inhibits viral RNA methylation and replication by stabilizing the cap-binding pocket through SAH binding. Additionally, RU-0415529 exhibits anti-infective activity in mouse models.

SARS-CoV, DNA Methyltransferase

Chromatin/Epigenetic, Microbiology/Virology

1358693

C21H29N3O4S

419.538

O=C(NCC=1C=CC=CC1OC)C2=CC(=C(N2C)C)S(=O)(=O)N3CCC(C)CC3

-20°C

Ice Packs

Small Compound