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RU-SKI 43 - CAS 1043797-53-0

RU-SKI 43 - CAS 1043797-53-0

MF-0015941-01

$43.64 USD
$43.64 USD
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Product Details

  • Bioactivity

    RU-SKI 43 is a potent and selective hedgehog acyltransferase (Hhat) inhibitor with an IC50 of 850 nM. It exhibits anticancer activity and is a potential treatment for lung adenocarcinomas. RU-SKI 43 reduces Gli-1 activation through smoothening-independent non-canonical signaling and inhibits Akt and mTOR pathway activity.

  • Target

    Hedgehog/Smoothened, Acyltransferase

  • Related Pathways

    GPCR/G Protein, Metabolism, Stem Cells

  • CAS Number

    1043744

  • Purity

    0.9985

  • Molecular Formula

    C22H30N2O2S

  • Molecular Weight

    386.55

  • SMILES

    C(OC1=CC(C)=CC=C1)C2C3=C(CCN2C(CNCC(CC)C)=O)SC=C3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound