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Molfinity

Rubone - CAS 73694-15-2

Rubone - CAS 73694-15-2

MF-0045635-01

$48.87 USD
$48.87 USD
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Product Details

  • Bioactivity

    Rubone (2'-Hydroxy-2,4,4',5,6'-pentamethoxychalcone), a natural product and a modulator of miR-34a (microRNA-34), upregulates miR-34a expression in a p53-dependent manner, which in turn downregulates the expression of downstream targets Bcl-2, cyclin-D1, CDK6, SIRT1, and FOXP1, thereby inhibiting tumor growth and reversal of hepatocellular carcinoma (HCC) and chemoresistance in prostate cancer.

  • Target

    MicroRNA

  • Related Pathways

    Chromatin/Epigenetic

  • CAS Number

    73677

  • Purity

    0.9892

  • Molecular Formula

    C20H22O7

  • Molecular Weight

    374.38

  • SMILES

    C(=C/C(=O)C1=C(OC)C=C(OC)C=C1O)\C2=C(OC)C=C(OC)C(OC)=C2

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Natural Product