Ruboxistaurin mesylate - CAS 192050-59-2

Ruboxistaurin is a PKC beta inhibitor. Ruboxistaurin reduces oxidative stress and attenuates left ventricular hypertrophy and dysfunction in rats with streptozotocin-induced diabetes. Ruboxistaurin attenuates diabetic nephropathy via modulation of TGF-β1/Smad and GRAP pathways. Ruboxistaurin inhibits retinal neovascularization via suppression of phosphorylation of ERK1/2 and Akt.

Others, PKC

Cytoskeletal Signaling, Chromatin/Epigenetic, Others

191989

C29H32N4O6S

564.65

S(C)(=O)(=O)O.O=C1C2=C(C=3C=4C(N(C3)CCO[C@H](CN(C)C)CCN5C=C2C=6C5=CC=CC6)=CC=CC4)C(=O)N1

-20°C

Ice Packs

Small Compound