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Rucaparib - CAS 283173-50-2

Rucaparib - CAS 283173-50-2

SKU:MF-0013982-01

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  • Bioactivity

    Rucaparib (PF-01367338) is a PARP protein inhibitor (PARP-1 Ki=1.4 nM) and hexose hexose-6-phosphate dehydrogenase (H6PD) inhibitor with oral activity. Rucaparib exhibits antitumor activity, with activity against desmoplasia-resistant prostate cancer (CRPC) .

  • Target

    PARP

  • Related Pathways

    DNA Damage/DNA Repair, Chromatin/Epigenetic

  • CAS Number

    283121

  • Purity

    0.9989

  • Molecular Formula

    C19H18FN3O

  • Molecular Weight

    323.36

  • SMILES

    O=C1C2=C3C(=C(NC3=CC(F)=C2)C4=CC=C(CNC)C=C4)CCN1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound